BDBM50500106 CHEMBL3741673

SMILES: Oc1c(cc(Br)c2ccccc12)C(Nc1ccccc1)c1ccccc1

InChI Key: InChIKey=OCSHEBWCPJBUQL-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50500106   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prenyl protein specific protease (Homo sapiens (Human))	BDBM50500106 (CHEMBL3741673) Show SMILES Oc1c(cc(Br)c2ccccc12)C(Nc1ccccc1)c1ccccc1 Show InChI InChI=1S/C23H18BrNO/c24-21-15-20(23(26)19-14-8-7-13-18(19)21)22(16-9-3-1-4-10-16)25-17-11-5-2-6-12-17/h1-15,22,25-26H	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
New York University Abu Dhabi Curated by ChEMBL					Assay Description Inhibition of human Rce1-mediated CaaX protease activity using ABZ-KSKTKC(farnesyl)QIIM and ABZ-KSKTKC(farnesyl)VIQI as substrate assessed as residua...				Bioorg Med Chem 24: 160-78 (2016) Article DOI: 10.1016/j.bmc.2015.11.043 BindingDB Entry DOI: 10.7270/Q2NS0XXQ
					More data for this Ligand-Target Pair