BDBM50500107 CHEMBL3741464

SMILES: Oc1c(ccc2cccnc12)C(Nc1ccccc1)c1ccccc1

InChI Key: InChIKey=OTNAVATYWOEDMK-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50500107   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein Disulfide-Isomerase (PDI) (Homo sapiens (Human))	BDBM50500107 (CHEMBL3741464) Show SMILES Oc1c(ccc2cccnc12)C(Nc1ccccc1)c1ccccc1 Show InChI InChI=1S/C22H18N2O/c25-22-19(14-13-17-10-7-15-23-21(17)22)20(16-8-3-1-4-9-16)24-18-11-5-2-6-12-18/h1-15,20,24-25H	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem		n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Prenyl protein specific protease (Homo sapiens (Human))	BDBM50500107 (CHEMBL3741464) Show SMILES Oc1c(ccc2cccnc12)C(Nc1ccccc1)c1ccccc1 Show InChI InChI=1S/C22H18N2O/c25-22-19(14-13-17-10-7-15-23-21(17)22)20(16-8-3-1-4-9-16)24-18-11-5-2-6-12-18/h1-15,20,24-25H	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
New York University Abu Dhabi Curated by ChEMBL					Assay Description Inhibition of human Rce1-mediated CaaX protease activity using ABZ-KSKTKC(farnesyl)QIIM and ABZ-KSKTKC(farnesyl)VIQI as substrate assessed as residua...				Bioorg Med Chem 24: 160-78 (2016) Article DOI: 10.1016/j.bmc.2015.11.043 BindingDB Entry DOI: 10.7270/Q2NS0XXQ
					More data for this Ligand-Target Pair