BDBM50500108 CHEMBL3740917

SMILES: OC(=O)c1ccc(NC(c2ccc(cc2)C#N)c2ccc3cccnc3c2O)cc1

InChI Key: InChIKey=YHIFRUGWHRCQLL-UHFFFAOYSA-N

Data: 1 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50500108   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prenyl protein specific protease (Homo sapiens (Human))	BDBM50500108 (CHEMBL3740917) Show SMILES OC(=O)c1ccc(NC(c2ccc(cc2)C#N)c2ccc3cccnc3c2O)cc1 Show InChI InChI=1S/C24H17N3O3/c25-14-15-3-5-17(6-4-15)21(27-19-10-7-18(8-11-19)24(29)30)20-12-9-16-2-1-13-26-22(16)23(20)28/h1-13,21,27-28H,(H,29,30)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
New York University Abu Dhabi Curated by ChEMBL					Assay Description Inhibition of human Rce1-mediated CaaX protease activity using ABZ-KSKTKC(farnesyl)QIIM and ABZ-KSKTKC(farnesyl)VIQI as substrate assessed as residua...				Bioorg Med Chem 24: 160-78 (2016) Article DOI: 10.1016/j.bmc.2015.11.043 BindingDB Entry DOI: 10.7270/Q2NS0XXQ
					More data for this Ligand-Target Pair