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SMILES: OC(=O)C(F)(F)F.N\C(NCCC[C@@H](NC(=O)C(c1ccccc1)c1ccccc1)C(=O)NCc1ccc(O)cc1)=N\C(=O)NCc1cn(nn1)-c1ccc(N)cc1

InChI Key: InChIKey=JWCYTMCTVWVWLY-RYWNGCACSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50500163   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Neuropeptide Y receptor type 1


(Homo sapiens (Human))		BDBM50500163
PNG
(CHEMBL3747224)
Show SMILES OC(=O)C(F)(F)F.N\C(NCCC[C@@H](NC(=O)C(c1ccccc1)c1ccccc1)C(=O)NCc1ccc(O)cc1)=N\C(=O)NCc1cn(nn1)-c1ccc(N)cc1 |r|
Show InChI InChI=1S/C37H40N10O4.C2HF3O2/c38-28-15-17-30(18-16-28)47-24-29(45-46-47)23-42-37(51)44-36(39)40-21-7-12-32(34(49)41-22-25-13-19-31(48)20-14-25)43-35(50)33(26-8-3-1-4-9-26)27-10-5-2-6-11-27;3-2(4,5)1(6)7/h1-6,8-11,13-20,24,32-33,48H,7,12,21-23,38H2,(H,41,49)(H,43,50)(H4,39,40,42,44,51);(H,6,7)/t32-;/m1./s1
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 4n/an/an/an/an/an/an/an/a



CNRS/IPBS (Institut de Pharmacologie et Biologie Structurale)

Curated by ChEMBL


Assay Description
Displacement of [3H]UR-MK114 from NPY1R in human SK-N-MC cells by radioligand binding assay

J Med Chem 58: 8834-49 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00925
BindingDB Entry DOI: 10.7270/Q2RN3BVG
More data for this
Ligand-Target Pair