BDBM50500368 CHEMBL3746595

SMILES: OCc1cc(Oc2ccc3n(ccc3c2)C(=O)Nc2cccc(c2)C(F)(F)F)ncn1

InChI Key: InChIKey=KSNTWEXIIUNPMO-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50500368   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50500368 (CHEMBL3746595) Show SMILES OCc1cc(Oc2ccc3n(ccc3c2)C(=O)Nc2cccc(c2)C(F)(F)F)ncn1 Show InChI InChI=1S/C21H15F3N4O3/c22-21(23,24)14-2-1-3-15(9-14)27-20(30)28-7-6-13-8-17(4-5-18(13)28)31-19-10-16(11-29)25-12-26-19/h1-10,12,29H,11H2,(H,27,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for BioMedical Research Curated by ChEMBL					Assay Description Inhibition of KDR (unknown origin)				J Med Chem 58: 9273-86 (2015) Article DOI: 10.1021/acs.jmedchem.5b01227 BindingDB Entry DOI: 10.7270/Q26M39T9
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50500368 (CHEMBL3746595) Show SMILES OCc1cc(Oc2ccc3n(ccc3c2)C(=O)Nc2cccc(c2)C(F)(F)F)ncn1 Show InChI InChI=1S/C21H15F3N4O3/c22-21(23,24)14-2-1-3-15(9-14)27-20(30)28-7-6-13-8-17(4-5-18(13)28)31-19-10-16(11-29)25-12-26-19/h1-10,12,29H,11H2,(H,27,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for BioMedical Research Curated by ChEMBL					Assay Description Inhibition of Tel-fused KDR (unknown origin) expressed in mouse BaF3 cells using poly(Glu,Tyr) as substrate after 10 mins by scintillation counting a...				J Med Chem 58: 9273-86 (2015) Article DOI: 10.1021/acs.jmedchem.5b01227 BindingDB Entry DOI: 10.7270/Q26M39T9
					More data for this Ligand-Target Pair