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SMILES: FCCOc1ccc(cc1)-c1cn(nn1)[C@H]1CN2CCC1CC2

InChI Key: InChIKey=GWUDLKZTESFCKI-KRWDZBQOSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50500416   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Neuronal acetylcholine receptor subunit alpha-7


(Rattus norvegicus (Rat))		BDBM50500416
PNG
(CHEMBL3747684)
Show SMILES FCCOc1ccc(cc1)-c1cn(nn1)[C@H]1CN2CCC1CC2 |r,wD:15.16,(-6.86,7.21,;-5.63,7.16,;-4.91,5.8,;-3.37,5.75,;-2.65,4.39,;-1.11,4.33,;-.39,2.97,;-1.2,1.67,;-2.75,1.72,;-3.47,3.08,;-.59,.25,;.92,-.08,;1.05,-1.6,;-.35,-2.23,;-1.37,-1.07,;2.43,-2.41,;2.41,-4.03,;3.81,-4.83,;5.21,-4.01,;5.21,-2.38,;3.81,-1.57,;3.26,-2.74,;4.33,-3.38,)|
Show InChI InChI=1S/C17H21FN4O/c18-7-10-23-15-3-1-13(2-4-15)16-11-22(20-19-16)17-12-21-8-5-14(17)6-9-21/h1-4,11,14,17H,5-10,12H2/t17-/m0/s1
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PC cid
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 190n/an/an/an/an/an/an/an/a



Universite Orleans

Curated by ChEMBL


Assay Description
Displacement of [125I]alpha-bungarotoxin from alpha7 nAchR in rat frontal cortices

Eur J Med Chem 107: 153-64 (2016)


Article DOI: 10.1016/j.ejmech.2015.11.001
BindingDB Entry DOI: 10.7270/Q2TF01CW
More data for this
Ligand-Target Pair