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SMILES: Fc1ccc(cn1)-c1cn(nn1)[C@H]1CN2CCC1CC2

InChI Key: InChIKey=BFHAQTHGFRDUIW-ZDUSSCGKSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50500431   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Neuronal acetylcholine receptor subunit alpha-7


(Rattus norvegicus (Rat))		BDBM50500431
PNG
(CHEMBL3746362)
Show SMILES Fc1ccc(cn1)-c1cn(nn1)[C@H]1CN2CCC1CC2 |r,wD:12.13,(-3.22,5.47,;-2.65,4.39,;-3.47,3.08,;-2.75,1.72,;-1.2,1.67,;-.39,2.97,;-1.11,4.33,;-.59,.25,;.92,-.08,;1.05,-1.6,;-.35,-2.23,;-1.37,-1.07,;2.43,-2.41,;2.41,-4.03,;3.81,-4.83,;5.21,-4.01,;5.21,-2.38,;3.81,-1.57,;3.26,-2.74,;4.33,-3.38,)|
Show InChI InChI=1S/C14H16FN5/c15-14-2-1-11(7-16-14)12-8-20(18-17-12)13-9-19-5-3-10(13)4-6-19/h1-2,7-8,10,13H,3-6,9H2/t13-/m0/s1
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PC cid
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Article
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 469n/an/an/an/an/an/an/an/a



Universite Orleans

Curated by ChEMBL


Assay Description
Displacement of [125I]alpha-bungarotoxin from alpha7 nAchR in rat frontal cortices

Eur J Med Chem 107: 153-64 (2016)


Article DOI: 10.1016/j.ejmech.2015.11.001
BindingDB Entry DOI: 10.7270/Q2TF01CW
More data for this
Ligand-Target Pair