BDBM50500687 CHEMBL3754289
SMILES: CCN(Cc1cccc2[nH]c3cc(OC)ccc3c12)C(=O)\C=C\c1ccc(O)c(OC)c1
InChI Key: InChIKey=UHESTEZGCGWYTJ-UKTHLTGXSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cholinesterase (Equus caballus (Horse)) | BDBM50500687 (CHEMBL3754289) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.98E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Southeast University Curated by ChEMBL | Assay Description Inhibition of equine BChE using BTC as substrate preincubated for 5 mins followed by substrate addition measured after 2 mins by Ellman's assay | Bioorg Med Chem 24: 886-93 (2016) Article DOI: 10.1016/j.bmc.2016.01.010 BindingDB Entry DOI: 10.7270/Q23R0WWJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acetylcholinesterase (Electrophorus electricus (Electric eel)) | BDBM50500687 (CHEMBL3754289) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 6.16E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Southeast University Curated by ChEMBL | Assay Description Inhibition of electric eel AChE using ATC as substrate preincubated for 5 mins followed by substrate addition measured after 2 mins by Ellman's assay | Bioorg Med Chem 24: 886-93 (2016) Article DOI: 10.1016/j.bmc.2016.01.010 BindingDB Entry DOI: 10.7270/Q23R0WWJ | |||||||||||
More data for this Ligand-Target Pair |