Found 6 hits for monomerid = 50501598 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Cyclin-Dependent Kinase 4 (CDK4)
(Homo sapiens (Human)) | BDBM50501598
![PNG](/data/jpeg/tenK5050/BindingDB_50501598.png) (CHEMBL4103372)Show SMILES CCN1CCN(Cc2ccc(Nc3nccc(n3)-c3sc(NC4CCCC4)nc3C)nc2)CC1 Show InChI InChI=1S/C25H34N8S/c1-3-32-12-14-33(15-13-32)17-19-8-9-22(27-16-19)31-24-26-11-10-21(30-24)23-18(2)28-25(34-23)29-20-6-4-5-7-20/h8-11,16,20H,3-7,12-15,17H2,1-2H3,(H,28,29)(H,26,27,30,31) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| 6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of South Australia
Curated by ChEMBL
| Assay Description Inhibition of CDK4/cyclin D1 (unknown origin) in presence of [gamma-33P]-ATP by KINOMEscan assay |
J Med Chem 60: 1892-1915 (2017)
Article DOI: 10.1021/acs.jmedchem.6b01670 BindingDB Entry DOI: 10.7270/Q29Z97XG |
More data for this Ligand-Target Pair | |
CDK6/CycD3
(Homo sapiens (Human)) | BDBM50501598
![PNG](/data/jpeg/tenK5050/BindingDB_50501598.png) (CHEMBL4103372)Show SMILES CCN1CCN(Cc2ccc(Nc3nccc(n3)-c3sc(NC4CCCC4)nc3C)nc2)CC1 Show InChI InChI=1S/C25H34N8S/c1-3-32-12-14-33(15-13-32)17-19-8-9-22(27-16-19)31-24-26-11-10-21(30-24)23-18(2)28-25(34-23)29-20-6-4-5-7-20/h8-11,16,20H,3-7,12-15,17H2,1-2H3,(H,28,29)(H,26,27,30,31) | PDB
UniProtKB/SwissProt
antibodypedia antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| 9 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of South Australia
Curated by ChEMBL
| Assay Description Inhibition of CDK6/cyclin D3 (unknown origin) in presence of [gamma-33P]-ATP by KINOMEscan assay |
J Med Chem 60: 1892-1915 (2017)
Article DOI: 10.1021/acs.jmedchem.6b01670 BindingDB Entry DOI: 10.7270/Q29Z97XG |
More data for this Ligand-Target Pair | |
Cyclin-Dependent Kinase 7 (CDK7)
(Homo sapiens (Human)) | BDBM50501598
![PNG](/data/jpeg/tenK5050/BindingDB_50501598.png) (CHEMBL4103372)Show SMILES CCN1CCN(Cc2ccc(Nc3nccc(n3)-c3sc(NC4CCCC4)nc3C)nc2)CC1 Show InChI InChI=1S/C25H34N8S/c1-3-32-12-14-33(15-13-32)17-19-8-9-22(27-16-19)31-24-26-11-10-21(30-24)23-18(2)28-25(34-23)29-20-6-4-5-7-20/h8-11,16,20H,3-7,12-15,17H2,1-2H3,(H,28,29)(H,26,27,30,31) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| 211 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of South Australia
Curated by ChEMBL
| Assay Description Inhibition of CDK7/cyclin H (unknown origin) in presence of [gamma-33P]-ATP by KINOMEscan assay |
J Med Chem 60: 1892-1915 (2017)
Article DOI: 10.1021/acs.jmedchem.6b01670 BindingDB Entry DOI: 10.7270/Q29Z97XG |
More data for this Ligand-Target Pair | |
Cyclin-Dependent Kinase 2 (CDK2)
(Homo sapiens (Human)) | BDBM50501598
![PNG](/data/jpeg/tenK5050/BindingDB_50501598.png) (CHEMBL4103372)Show SMILES CCN1CCN(Cc2ccc(Nc3nccc(n3)-c3sc(NC4CCCC4)nc3C)nc2)CC1 Show InChI InChI=1S/C25H34N8S/c1-3-32-12-14-33(15-13-32)17-19-8-9-22(27-16-19)31-24-26-11-10-21(30-24)23-18(2)28-25(34-23)29-20-6-4-5-7-20/h8-11,16,20H,3-7,12-15,17H2,1-2H3,(H,28,29)(H,26,27,30,31) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| 416 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of South Australia
Curated by ChEMBL
| Assay Description Inhibition of CDK2/cyclin A (unknown origin) in presence of [gamma-33P]-ATP by KINOMEscan assay |
J Med Chem 60: 1892-1915 (2017)
Article DOI: 10.1021/acs.jmedchem.6b01670 BindingDB Entry DOI: 10.7270/Q29Z97XG |
More data for this Ligand-Target Pair | |
Cyclin-Dependent Kinase 9 (CDK9)
(Homo sapiens (Human)) | BDBM50501598
![PNG](/data/jpeg/tenK5050/BindingDB_50501598.png) (CHEMBL4103372)Show SMILES CCN1CCN(Cc2ccc(Nc3nccc(n3)-c3sc(NC4CCCC4)nc3C)nc2)CC1 Show InChI InChI=1S/C25H34N8S/c1-3-32-12-14-33(15-13-32)17-19-8-9-22(27-16-19)31-24-26-11-10-21(30-24)23-18(2)28-25(34-23)29-20-6-4-5-7-20/h8-11,16,20H,3-7,12-15,17H2,1-2H3,(H,28,29)(H,26,27,30,31) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| 1.98E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of South Australia
Curated by ChEMBL
| Assay Description Inhibition of CDK9/cyclin T1 (unknown origin) in presence of [gamma-33P]-ATP by KINOMEscan assay |
J Med Chem 60: 1892-1915 (2017)
Article DOI: 10.1021/acs.jmedchem.6b01670 BindingDB Entry DOI: 10.7270/Q29Z97XG |
More data for this Ligand-Target Pair | |
Cyclin-Dependent Kinase 1 (CDK1)
(Homo sapiens (Human)) | BDBM50501598
![PNG](/data/jpeg/tenK5050/BindingDB_50501598.png) (CHEMBL4103372)Show SMILES CCN1CCN(Cc2ccc(Nc3nccc(n3)-c3sc(NC4CCCC4)nc3C)nc2)CC1 Show InChI InChI=1S/C25H34N8S/c1-3-32-12-14-33(15-13-32)17-19-8-9-22(27-16-19)31-24-26-11-10-21(30-24)23-18(2)28-25(34-23)29-20-6-4-5-7-20/h8-11,16,20H,3-7,12-15,17H2,1-2H3,(H,28,29)(H,26,27,30,31) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| >5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of South Australia
Curated by ChEMBL
| Assay Description Inhibition of CDK1/cyclin B (unknown origin) in presence of [gamma-33P]-ATP by KINOMEscan assay |
J Med Chem 60: 1892-1915 (2017)
Article DOI: 10.1021/acs.jmedchem.6b01670 BindingDB Entry DOI: 10.7270/Q29Z97XG |
More data for this Ligand-Target Pair | |