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BDBM50501925 CHEMBL4472596

SMILES: [H][C@@]12C[C@@H](C[C@]1([H])CN(C2)C(=O)c1nnc2ccc(OCC)cn12)c1ccccc1C(F)(F)F

InChI Key: InChIKey=IFLISYPDFOMNGZ-PHZGNYQRSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50501925   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Retinol-binding protein 4


(Homo sapiens (Human))		BDBM50501925
PNG
(CHEMBL4472596)
Show SMILES [H][C@@]12C[C@@H](C[C@]1([H])CN(C2)C(=O)c1nnc2ccc(OCC)cn12)c1ccccc1C(F)(F)F |r|
Show InChI InChI=1S/C23H23F3N4O2/c1-2-32-17-7-8-20-27-28-21(30(20)13-17)22(31)29-11-15-9-14(10-16(15)12-29)18-5-3-4-6-19(18)23(24,25)26/h3-8,13-16H,2,9-12H2,1H3/t14-,15-,16+
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Article
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n/an/a 2.70n/an/an/an/an/an/a



Albany College of Pharmacy and Health Sciences

Curated by ChEMBL


Assay Description
Competitive displacement of 3[H]retinol from biotinylated RBP4 (unknown origin) by surface plasmon resonance analysis

J Med Chem 62: 5470-5500 (2019)


Article DOI: 10.1021/acs.jmedchem.9b00352
More data for this
Ligand-Target Pair