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SMILES: Cc1cccc(c1)-c1cnc2[nH]cc(NC(=O)c3cccnc3)c2c1

InChI Key: InChIKey=AJKZJGFDHDTOSH-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50502304   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
AP2-associated protein kinase 1


(Homo sapiens (Human))		BDBM50502304
PNG
(CHEMBL4483684)
Show SMILES Cc1cccc(c1)-c1cnc2[nH]cc(NC(=O)c3cccnc3)c2c1
Show InChI InChI=1S/C20H16N4O/c1-13-4-2-5-14(8-13)16-9-17-18(12-23-19(17)22-11-16)24-20(25)15-6-3-7-21-10-15/h2-12H,1H3,(H,22,23)(H,24,25)
PDB

KEGG

UniProtKB/SwissProt

antibodypedia
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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 19n/an/an/an/an/an/a



KU Leuven

Curated by ChEMBL


Assay Description
Displacement of tracer 222 from GST-tagged recombinant human AAK1 catalytic domain (1 to 510 amino acids) expressed in insect cells shaken for 30 sec...

J Med Chem 62: 5810-5831 (2019)


Article DOI: 10.1021/acs.jmedchem.9b00136
More data for this
Ligand-Target Pair