null

SMILES: Fc1ccc2nc(-c3cnccn3)n(C3CC3)c2c1

InChI Key: InChIKey=BUOZLPPJCBYBIM-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50502514   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytochrome P450 11B2, mitochondrial (Homo sapiens (Human))	BDBM50502514 (CHEMBL4577872) Show SMILES Fc1ccc2nc(-c3cnccn3)n(C3CC3)c2c1 Show InChI InChI=1S/C14H11FN4/c15-9-1-4-11-13(7-9)19(10-2-3-10)14(18-11)12-8-16-5-6-17-12/h1,4-8,10H,2-3H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	541	n/a	n/a	n/a	n/a	n/a	n/a
Selenity Therapeutics Curated by ChEMBL					Assay Description Inhibition of human recombinant CYP11B2 using deoxycorticosterone as substrate incubated for 90 mins by cell-based HPLC analysis				ACS Med Chem Lett 10: 1056-1060 (2019) Article DOI: 10.1021/acsmedchemlett.9b00152
					More data for this Ligand-Target Pair
Cytochrome P450 11B1, mitochondrial (Homo sapiens (Human))	BDBM50502514 (CHEMBL4577872) Show SMILES Fc1ccc2nc(-c3cnccn3)n(C3CC3)c2c1 Show InChI InChI=1S/C14H11FN4/c15-9-1-4-11-13(7-9)19(10-2-3-10)14(18-11)12-8-16-5-6-17-12/h1,4-8,10H,2-3H2	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Selenity Therapeutics Curated by ChEMBL					Assay Description Inhibition of human recombinant CYP11B1 using deoxycortisol as substrate incubated for 60 mins by cell-based HPLC analysis				ACS Med Chem Lett 10: 1056-1060 (2019) Article DOI: 10.1021/acsmedchemlett.9b00152
					More data for this Ligand-Target Pair