Found 4 hits for monomerid = 50502834 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Procathepsin L
(Homo sapiens (Human)) | BDBM50502834
(CHEMBL4442543)Show SMILES CC(C)C[C@H](NC(=O)c1ccccc1)C(=O)NC1(CC1)C#N |r| Show InChI InChI=1S/C17H21N3O2/c1-12(2)10-14(16(22)20-17(11-18)8-9-17)19-15(21)13-6-4-3-5-7-13/h3-7,12,14H,8-10H2,1-2H3,(H,19,21)(H,20,22)/t14-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | 20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this Ligand-Target Pair | |
Procathepsin L
(Homo sapiens (Human)) | BDBM50502834
(CHEMBL4442543)Show SMILES CC(C)C[C@H](NC(=O)c1ccccc1)C(=O)NC1(CC1)C#N |r| Show InChI InChI=1S/C17H21N3O2/c1-12(2)10-14(16(22)20-17(11-18)8-9-17)19-15(21)13-6-4-3-5-7-13/h3-7,12,14H,8-10H2,1-2H3,(H,19,21)(H,20,22)/t14-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidade de S£o Paulo
Curated by ChEMBL
| Assay Description Inhibition of Cathepsin L (unknown origin) using Z-Phe-Arg-7-amido-4-methylcoumarin as substrate preincubated for 2 mins followed by susbtrate additi... |
Bioorg Med Chem 27: (2019)
Article DOI: 10.1016/j.bmc.2019.115083 |
More data for this Ligand-Target Pair | |
Cruzipain
(Trypanosoma cruzi) | BDBM50502834
(CHEMBL4442543)Show SMILES CC(C)C[C@H](NC(=O)c1ccccc1)C(=O)NC1(CC1)C#N |r| Show InChI InChI=1S/C17H21N3O2/c1-12(2)10-14(16(22)20-17(11-18)8-9-17)19-15(21)13-6-4-3-5-7-13/h3-7,12,14H,8-10H2,1-2H3,(H,19,21)(H,20,22)/t14-/m0/s1 | PDB MMDB
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank GoogleScholar AffyNet
| PC cid PC sid UniChem
| | 50 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this Ligand-Target Pair | |
Cruzipain
(Trypanosoma cruzi) | BDBM50502834
(CHEMBL4442543)Show SMILES CC(C)C[C@H](NC(=O)c1ccccc1)C(=O)NC1(CC1)C#N |r| Show InChI InChI=1S/C17H21N3O2/c1-12(2)10-14(16(22)20-17(11-18)8-9-17)19-15(21)13-6-4-3-5-7-13/h3-7,12,14H,8-10H2,1-2H3,(H,19,21)(H,20,22)/t14-/m0/s1 | PDB MMDB
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 50 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidade de S£o Paulo
Curated by ChEMBL
| Assay Description Inhibition of Trypanosoma cruzi cruzain using Z-Phe-Arg-7-amido-4-methylcoumarin as substrate preincubated for 2 mins followed by susbtrate addition ... |
Bioorg Med Chem 27: (2019)
Article DOI: 10.1016/j.bmc.2019.115083 |
More data for this Ligand-Target Pair | |