BDBM50503007 CHEMBL4446123

SMILES: CCOC(=O)c1ncc([nH]1)-c1ccnc(NC(=O)C2CC2)c1

InChI Key: InChIKey=NKBCCNZDWTXALB-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50503007   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50503007 (CHEMBL4446123) Show SMILES CCOC(=O)c1ncc([nH]1)-c1ccnc(NC(=O)C2CC2)c1 Show InChI InChI=1S/C15H16N4O3/c1-2-22-15(21)13-17-8-11(18-13)10-5-6-16-12(7-10)19-14(20)9-3-4-9/h5-9H,2-4H2,1H3,(H,17,18)(H,16,19,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard Karls Universit£t T£bingen Curated by ChEMBL					Assay Description Inhibition of P38alpha MAPK (unknown origin) by ADP-Glo assay				ACS Med Chem Lett 10: 1407-1414 (2019) Article DOI: 10.1021/acsmedchemlett.9b00177
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50503007 (CHEMBL4446123) Show SMILES CCOC(=O)c1ncc([nH]1)-c1ccnc(NC(=O)C2CC2)c1 Show InChI InChI=1S/C15H16N4O3/c1-2-22-15(21)13-17-8-11(18-13)10-5-6-16-12(7-10)19-14(20)9-3-4-9/h5-9H,2-4H2,1H3,(H,17,18)(H,16,19,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	739	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard Karls Universit£t T£bingen Curated by ChEMBL					Assay Description Inhibition of GSK3beta (unknown origin) by ADP-Glo assay				ACS Med Chem Lett 10: 1407-1414 (2019) Article DOI: 10.1021/acsmedchemlett.9b00177
					More data for this Ligand-Target Pair