BDBM50503139 CHEMBL1242115

SMILES: CC(C)n1nc(-c2cccc(c2)C(=O)NC2=NCCS2)c2c(N)ncnc12

InChI Key: InChIKey=WGYPOAXANMFHMT-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50503139   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Target of rapamycin complex subunit LST8 (Homo sapiens)	BDBM50503139 (CHEMBL1242115) Show SMILES CC(C)n1nc(-c2cccc(c2)C(=O)NC2=NCCS2)c2c(N)ncnc12 |t:16| Show InChI InChI=1S/C18H19N7OS/c1-10(2)25-16-13(15(19)21-9-22-16)14(24-25)11-4-3-5-12(8-11)17(26)23-18-20-6-7-27-18/h3-5,8-10H,6-7H2,1-2H3,(H2,19,21,22)(H,20,23,26)	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of mTORC1 (unknown origin)				J Med Chem 61: 4656-4687 (2018) Article DOI: 10.1021/acs.jmedchem.7b01019
					More data for this Ligand-Target Pair
Target of rapamycin complex 2 subunit MAPKAP1 (Homo sapiens)	BDBM50503139 (CHEMBL1242115) Show SMILES CC(C)n1nc(-c2cccc(c2)C(=O)NC2=NCCS2)c2c(N)ncnc12 |t:16| Show InChI InChI=1S/C18H19N7OS/c1-10(2)25-16-13(15(19)21-9-22-16)14(24-25)11-4-3-5-12(8-11)17(26)23-18-20-6-7-27-18/h3-5,8-10H,6-7H2,1-2H3,(H2,19,21,22)(H,20,23,26)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of mTORC2 (unknown origin)				J Med Chem 61: 4656-4687 (2018) Article DOI: 10.1021/acs.jmedchem.7b01019
					More data for this Ligand-Target Pair