BDBM50503153 CHEMBL4544421

SMILES: CCN(CC)C(=S)Oc1ccc(cc1)C(=O)Nc1cccc2ccccc12

InChI Key: InChIKey=GREQUCSPWQUZPQ-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50503153   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ionotropic glutamate receptor NMDA 1/2C (Homo sapiens (Human))	BDBM50503153 (CHEMBL4544421) Show SMILES CCN(CC)C(=S)Oc1ccc(cc1)C(=O)Nc1cccc2ccccc12 Show InChI InChI=1S/C22H22N2O2S/c1-3-24(4-2)22(27)26-18-14-12-17(13-15-18)21(25)23-20-11-7-9-16-8-5-6-10-19(16)20/h5-15H,3-4H2,1-2H3,(H,23,25)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Bristol Curated by ChEMBL					Assay Description Negative allosteric modulation of GluN2C receptor (unknown origin) expressed in xenopus laevis oocytes assessed as reduction in glycine-induced chann...				J Med Chem 62: 3-23 (2019) Article DOI: 10.1021/acs.jmedchem.7b01640
					More data for this Ligand-Target Pair
Ionotropic glutamate receptor NMDA 1/2D (Homo sapiens (Human))	BDBM50503153 (CHEMBL4544421) Show SMILES CCN(CC)C(=S)Oc1ccc(cc1)C(=O)Nc1cccc2ccccc12 Show InChI InChI=1S/C22H22N2O2S/c1-3-24(4-2)22(27)26-18-14-12-17(13-15-18)21(25)23-20-11-7-9-16-8-5-6-10-19(16)20/h5-15H,3-4H2,1-2H3,(H,23,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Bristol Curated by ChEMBL					Assay Description Negative allosteric modulation of GluN2D receptor (unknown origin) expressed in xenopus laevis oocytes assessed as reduction in glycine-induced chann...				J Med Chem 62: 3-23 (2019) Article DOI: 10.1021/acs.jmedchem.7b01640
					More data for this Ligand-Target Pair