BDBM50503864 CHEMBL4573527

SMILES: Cc1cccc(c1)-c1ccc2C(=O)NCCc2c1

InChI Key: InChIKey=VWRQKYYMULSAJC-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50503864   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Poly [ADP-ribose] polymerase 11 (Homo sapiens)	BDBM50503864 (CHEMBL4573527) Show SMILES Cc1cccc(c1)-c1ccc2C(=O)NCCc2c1 Show InChI InChI=1S/C16H15NO/c1-11-3-2-4-12(9-11)13-5-6-15-14(10-13)7-8-17-16(15)18/h2-6,9-10H,7-8H2,1H3,(H,17,18)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.57E+3	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of full length human His-SUMO-tagged PARP11 expressed in Escherichia coli BL21 assessed as reduction in MARylation of His6-tagged SRPK2 su...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429
					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 10 (Homo sapiens (Human))	BDBM50503864 (CHEMBL4573527) Show SMILES Cc1cccc(c1)-c1ccc2C(=O)NCCc2c1 Show InChI InChI=1S/C16H15NO/c1-11-3-2-4-12(9-11)13-5-6-15-14(10-13)7-8-17-16(15)18/h2-6,9-10H,7-8H2,1H3,(H,17,18)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.14E+3	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of human PARP10 catalytic domain assessed as reduction in MARylation of His6-tagged SRPK2 substrate after 60 mins in presence of NAD+ by c...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429
					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 11 (Homo sapiens)	BDBM50503864 (CHEMBL4573527) Show SMILES Cc1cccc(c1)-c1ccc2C(=O)NCCc2c1 Show InChI InChI=1S/C16H15NO/c1-11-3-2-4-12(9-11)13-5-6-15-14(10-13)7-8-17-16(15)18/h2-6,9-10H,7-8H2,1H3,(H,17,18)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of full length human His-SUMO-tagged PARP11 expressed in Escherichia coli BL21 assessed as reduction in MARylation of His6-tagged SRPK2 su...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429
					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 10 (Homo sapiens (Human))	BDBM50503864 (CHEMBL4573527) Show SMILES Cc1cccc(c1)-c1ccc2C(=O)NCCc2c1 Show InChI InChI=1S/C16H15NO/c1-11-3-2-4-12(9-11)13-5-6-15-14(10-13)7-8-17-16(15)18/h2-6,9-10H,7-8H2,1H3,(H,17,18)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health and Science University Curated by ChEMBL					Assay Description Inhibition of human PARP10 catalytic domain assessed as reduction in MARylation of His6-tagged SRPK2 substrate after 60 mins in presence of NAD+ by c...				ACS Med Chem Lett 10: 74-79 (2019) Article DOI: 10.1021/acsmedchemlett.8b00429
					More data for this Ligand-Target Pair