BDBM50504679 CHEMBL4569049

SMILES: Cl.COc1ccccc1\C=C\C(=O)c1cccc(OCCCN2CCOCC2)c1

InChI Key: InChIKey=KONPCHCZUTYFPV-ZHACJKMWSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50504679   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nuclear factor erythroid 2-related factor 2 (Homo sapiens (Human))	BDBM50504679 (CHEMBL4569049) Show SMILES Cl.COc1ccccc1\C=C\C(=O)c1cccc(OCCCN2CCOCC2)c1 Show InChI InChI=1S/C23H27NO4/c1-26-23-9-3-2-6-19(23)10-11-22(25)20-7-4-8-21(18-20)28-15-5-12-24-13-16-27-17-14-24/h2-4,6-11,18H,5,12-17H2,1H3/b11-10+	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.72E+3	n/a	n/a	n/a	n/a
Korea Institute of Science and Technology (KIST) Curated by ChEMBL					Assay Description Activation of NRF2 in human U2OS cells co-expressing Keap1 (unknown origin) assessed as induction of NRF2 translocation to nucleus incubated for 6 hr...				Eur J Med Chem 185: (2020) Article DOI: 10.1016/j.ejmech.2019.111777
					More data for this Ligand-Target Pair