BDBM50504968 CHEMBL4517939

SMILES: COc1cc(ccc1Cl)-c1nn(c(N)c1C(N)=O)C(C)(C)C

InChI Key: InChIKey=SFIBOCKHYAEQFC-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50504968   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase RIPK2 (Homo sapiens (Human))	BDBM50504968 (CHEMBL4517939) Show SMILES COc1cc(ccc1Cl)-c1nn(c(N)c1C(N)=O)C(C)(C)C Show InChI InChI=1S/C15H19ClN4O2/c1-15(2,3)20-13(17)11(14(18)21)12(19-20)8-5-6-9(16)10(7-8)22-4/h5-7H,17H2,1-4H3,(H2,18,21)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of full length FLAG/His-tagged RIPK2 (unknown origin) expressed in baculovirus expression system after 10 mins by fluorescent polarization...				ACS Med Chem Lett 10: 1518-1523 (2019) Article DOI: 10.1021/acsmedchemlett.9b00141
					More data for this Ligand-Target Pair