BDBM50504973 CHEMBL4461710

SMILES: CC(C)(C)n1nc(c(C(N)=O)c1N)-c1ccc2nonc2c1

InChI Key: InChIKey=KDNJFMNUKJXHLX-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50504973   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase RIPK2 (Homo sapiens (Human))	BDBM50504973 (CHEMBL4461710) Show SMILES CC(C)(C)n1nc(c(C(N)=O)c1N)-c1ccc2nonc2c1 Show InChI InChI=1S/C14H16N6O2/c1-14(2,3)20-12(15)10(13(16)21)11(17-20)7-4-5-8-9(6-7)19-22-18-8/h4-6H,15H2,1-3H3,(H2,16,21)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	790	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of full length FLAG/His-tagged RIPK2 (unknown origin) expressed in baculovirus expression system after 10 mins by fluorescent polarization...				ACS Med Chem Lett 10: 1518-1523 (2019) Article DOI: 10.1021/acsmedchemlett.9b00141
					More data for this Ligand-Target Pair