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BDBM50505274 CHEMBL2315639

SMILES: OC(=O)C1CCCN(CCC\C=C\c2ccccc2-c2ccc(Cl)cc2Cl)C1

InChI Key: InChIKey=VLYVVKVWOZWWGI-FARCUNLSSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50505274   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Sodium- and chloride-dependent GABA transporter 1


(Rattus norvegicus)		BDBM50505274
PNG
(CHEMBL2315639)
Show SMILES OC(=O)C1CCCN(CCC\C=C\c2ccccc2-c2ccc(Cl)cc2Cl)C1
Show InChI InChI=1S/C23H25Cl2NO2/c24-19-11-12-21(22(25)15-19)20-10-4-3-8-17(20)7-2-1-5-13-26-14-6-9-18(16-26)23(27)28/h2-4,7-8,10-12,15,18H,1,5-6,9,13-14,16H2,(H,27,28)/b7-2+
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UniProtKB/SwissProt

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PC cid
PC sid
UniChem
Article
PubMed
 117n/an/an/an/an/an/an/an/a



Shandong University

Curated by ChEMBL


Assay Description
Inhibition of NO711 binding to mouse GAT1 receptor expressed in HEK293 cell membranes incubated for 1 hr by LC-ESI-MS/MS analysis

J Med Chem 62: 9375-9414 (2019)


Article DOI: 10.1021/acs.jmedchem.9b00359
More data for this
Ligand-Target Pair