BDBM50505555 CHEMBL4447348

SMILES: COC1=CC(=O)N([C@H]1CC(C)C)C(=O)\C=C\[C@H](Cc1ccccc1)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)OC(=O)[C@H](C(C)C)N(C)C

InChI Key: InChIKey=GVIHWZBKUKQYMN-GPSXOSEWSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50505555   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Procathepsin L (Homo sapiens (Human))	BDBM50505555 (CHEMBL4447348) Show SMILES COC1=CC(=O)N([C@H]1CC(C)C)C(=O)\C=C\[C@H](Cc1ccccc1)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)OC(=O)[C@H](C(C)C)N(C)C |r,t:2| Show InChI InChI=1S/C39H60N4O7/c1-24(2)19-30(41-38(47)33(21-26(5)6)50-39(48)36(27(7)8)42(9)10)37(46)40-29(22-28-15-13-12-14-16-28)17-18-34(44)43-31(20-25(3)4)32(49-11)23-35(43)45/h12-18,23-27,29-31,33,36H,19-22H2,1-11H3,(H,40,46)(H,41,47)/b18-17+/t29-,30+,31+,33+,36+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.632	n/a	n/a	n/a	n/a	n/a	n/a
The University of Jordan Curated by ChEMBL					Assay Description Inhibition of human cathepsin L using fluorogenic substrate cbz-FR-AMC monitored for 90 to 120 mins by spectrophotometry				J Med Chem 62: 9026-9044 (2019) Article DOI: 10.1021/acs.jmedchem.9b00294
					More data for this Ligand-Target Pair
Cruzipain (Trypanosoma cruzi)	BDBM50505555 (CHEMBL4447348) Show SMILES COC1=CC(=O)N([C@H]1CC(C)C)C(=O)\C=C\[C@H](Cc1ccccc1)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)OC(=O)[C@H](C(C)C)N(C)C |r,t:2| Show InChI InChI=1S/C39H60N4O7/c1-24(2)19-30(41-38(47)33(21-26(5)6)50-39(48)36(27(7)8)42(9)10)37(46)40-29(22-28-15-13-12-14-16-28)17-18-34(44)43-31(20-25(3)4)32(49-11)23-35(43)45/h12-18,23-27,29-31,33,36H,19-22H2,1-11H3,(H,40,46)(H,41,47)/b18-17+/t29-,30+,31+,33+,36+/m1/s1	PDB MMDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.25	n/a	n/a	n/a	n/a	n/a	n/a
The University of Jordan Curated by ChEMBL					Assay Description Inhibition of recombinant Trypanosoma cruzi Cruzain expressed in Pichia pastoris using Z-Phe-Arg-AMC substrate incubated for 30 mins by fluorescence ...				J Med Chem 62: 9026-9044 (2019) Article DOI: 10.1021/acs.jmedchem.9b00294
					More data for this Ligand-Target Pair