BDBM50505868 CHEMBL4537919

SMILES: C[C@H](NC(=O)c1ccc(C)c(NC(=O)c2ccc(s2)-c2ccccc2Cl)c1)C(N)=O

InChI Key: InChIKey=KDQUIWMZXDFLNF-ZDUSSCGKSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50505868   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50505868 (CHEMBL4537919) Show SMILES C[C@H](NC(=O)c1ccc(C)c(NC(=O)c2ccc(s2)-c2ccccc2Cl)c1)C(N)=O |r| Show InChI InChI=1S/C22H20ClN3O3S/c1-12-7-8-14(21(28)25-13(2)20(24)27)11-17(12)26-22(29)19-10-9-18(30-19)15-5-3-4-6-16(15)23/h3-11,13H,1-2H3,(H2,24,27)(H,25,28)(H,26,29)/t13-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	316	n/a	n/a	n/a	n/a	n/a	n/a
Johann Wolfgang Goethe-University Curated by ChEMBL					Assay Description Inhibition of recombinant human His-tagged P38 alpha MAPK (1 to 360 residues) expressed in Escherichia coli incubated for 60 mins by [gamma-33P]ATP b...				J Med Chem 62: 10757-10782 (2019) Article DOI: 10.1021/acs.jmedchem.9b01227
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 11 (Homo sapiens (Human))	BDBM50505868 (CHEMBL4537919) Show SMILES C[C@H](NC(=O)c1ccc(C)c(NC(=O)c2ccc(s2)-c2ccccc2Cl)c1)C(N)=O |r| Show InChI InChI=1S/C22H20ClN3O3S/c1-12-7-8-14(21(28)25-13(2)20(24)27)11-17(12)26-22(29)19-10-9-18(30-19)15-5-3-4-6-16(15)23/h3-11,13H,1-2H3,(H2,24,27)(H,25,28)(H,26,29)/t13-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Johann Wolfgang Goethe-University Curated by ChEMBL					Assay Description Inhibition of recombinant human His-tagged P38beta MAPK (1 to 364 residues) expressed in Escherichia coli incubated for 60 mins by [gamma-33P]ATP bas...				J Med Chem 62: 10757-10782 (2019) Article DOI: 10.1021/acs.jmedchem.9b01227
					More data for this Ligand-Target Pair