BDBM50505881 CHEMBL4447850

SMILES: Cc1ccccc1-n1cc(cn1)C(=O)NCc1ccc(cc1)C(=O)NC1CC1

InChI Key: InChIKey=ZWTVTWYFXGIJFS-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50505881   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
p38 MAP kinase alpha/beta (Homo sapiens (Human))	BDBM50505881 (CHEMBL4447850) Show SMILES Cc1ccccc1-n1cc(cn1)C(=O)NCc1ccc(cc1)C(=O)NC1CC1 Show InChI InChI=1S/C22H22N4O2/c1-15-4-2-3-5-20(15)26-14-18(13-24-26)21(27)23-12-16-6-8-17(9-7-16)22(28)25-19-10-11-19/h2-9,13-14,19H,10-12H2,1H3,(H,23,27)(H,25,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.18E+3	n/a	n/a	n/a	n/a	n/a	n/a
Johann Wolfgang Goethe-University Curated by ChEMBL					Assay Description Inhibition of recombinant human His-tagged P38beta MAPK (1 to 364 residues) expressed in Escherichia coli incubated for 60 mins by [gamma-33P]ATP bas...				J Med Chem 62: 10757-10782 (2019) Article DOI: 10.1021/acs.jmedchem.9b01227
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50505881 (CHEMBL4447850) Show SMILES Cc1ccccc1-n1cc(cn1)C(=O)NCc1ccc(cc1)C(=O)NC1CC1 Show InChI InChI=1S/C22H22N4O2/c1-15-4-2-3-5-20(15)26-14-18(13-24-26)21(27)23-12-16-6-8-17(9-7-16)22(28)25-19-10-11-19/h2-9,13-14,19H,10-12H2,1H3,(H,23,27)(H,25,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	280	n/a	n/a	n/a	n/a	n/a	n/a
Johann Wolfgang Goethe-University Curated by ChEMBL					Assay Description Inhibition of recombinant human His-tagged P38 alpha MAPK (1 to 360 residues) expressed in Escherichia coli incubated for 60 mins by [gamma-33P]ATP b...				J Med Chem 62: 10757-10782 (2019) Article DOI: 10.1021/acs.jmedchem.9b01227
					More data for this Ligand-Target Pair