BDBM50505915 CHEMBL4438679

SMILES: CC(NC(=O)c1cnn(c1)-c1ccccc1)c1ccc(cc1)C(=O)N[C@@H](CCC1CCCCC1)C(N)=O

InChI Key: InChIKey=RYEFPWKRHLKVLM-GHZUAHJPSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50505915   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50505915 (CHEMBL4438679) Show SMILES CC(NC(=O)c1cnn(c1)-c1ccccc1)c1ccc(cc1)C(=O)N[C@@H](CCC1CCCCC1)C(N)=O |r| Show InChI InChI=1S/C29H35N5O3/c1-20(32-29(37)24-18-31-34(19-24)25-10-6-3-7-11-25)22-13-15-23(16-14-22)28(36)33-26(27(30)35)17-12-21-8-4-2-5-9-21/h3,6-7,10-11,13-16,18-21,26H,2,4-5,8-9,12,17H2,1H3,(H2,30,35)(H,32,37)(H,33,36)/t20?,26-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	280	n/a	n/a	n/a	n/a	n/a	n/a
Johann Wolfgang Goethe-University Curated by ChEMBL					Assay Description Inhibition of recombinant human His-tagged P38 alpha MAPK (1 to 360 residues) expressed in Escherichia coli incubated for 60 mins by [gamma-33P]ATP b...				J Med Chem 62: 10757-10782 (2019) Article DOI: 10.1021/acs.jmedchem.9b01227
					More data for this Ligand-Target Pair
p38 MAP kinase alpha/beta (Homo sapiens (Human))	BDBM50505915 (CHEMBL4438679) Show SMILES CC(NC(=O)c1cnn(c1)-c1ccccc1)c1ccc(cc1)C(=O)N[C@@H](CCC1CCCCC1)C(N)=O |r| Show InChI InChI=1S/C29H35N5O3/c1-20(32-29(37)24-18-31-34(19-24)25-10-6-3-7-11-25)22-13-15-23(16-14-22)28(36)33-26(27(30)35)17-12-21-8-4-2-5-9-21/h3,6-7,10-11,13-16,18-21,26H,2,4-5,8-9,12,17H2,1H3,(H2,30,35)(H,32,37)(H,33,36)/t20?,26-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.05E+3	n/a	n/a	n/a	n/a	n/a	n/a
Johann Wolfgang Goethe-University Curated by ChEMBL					Assay Description Inhibition of recombinant human His-tagged P38beta MAPK (1 to 364 residues) expressed in Escherichia coli incubated for 60 mins by [gamma-33P]ATP bas...				J Med Chem 62: 10757-10782 (2019) Article DOI: 10.1021/acs.jmedchem.9b01227
					More data for this Ligand-Target Pair