BDBM50506025 CHEMBL4454971

SMILES: CCC[C@@H](NC(=O)c1ccc(c(c1)C(O)=O)-c1cc(Cl)ccc1-c1nc2cc(C)ccc2[nH]1)c1ccccc1

InChI Key: InChIKey=IBBGIFWIAFIMHZ-HHHXNRCGSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50506025   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Apelin receptor (Homo sapiens (Human))	BDBM50506025 (CHEMBL4454971) Show SMILES CCC[C@@H](NC(=O)c1ccc(c(c1)C(O)=O)-c1cc(Cl)ccc1-c1nc2cc(C)ccc2[nH]1)c1ccccc1 |r| Show InChI InChI=1S/C32H28ClN3O3/c1-3-7-27(20-8-5-4-6-9-20)36-31(37)21-11-13-23(26(17-21)32(38)39)25-18-22(33)12-14-24(25)30-34-28-15-10-19(2)16-29(28)35-30/h4-6,8-18,27H,3,7H2,1-2H3,(H,34,35)(H,36,37)(H,38,39)/t27-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	0.600	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Agonist activity at human APJ-R expressed in HEK293 cells assessed as inhibition of forskolin- stimulated cAMP accumulation incubated for 30 mins by ...				J Med Chem 62: 10456-10465 (2019) Article DOI: 10.1021/acs.jmedchem.9b01513
					More data for this Ligand-Target Pair