BDBM50506030 CHEMBL4565753

SMILES: CCC[C@@H](NC(=O)c1ccc(c(c1)C(O)=O)-c1ccccc1-c1nc2ccccc2[nH]1)c1ccccc1

InChI Key: InChIKey=SHVOLFBKUFZKOC-AREMUKBSSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50506030   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Apelin receptor (Homo sapiens (Human))	BDBM50506030 (CHEMBL4565753) Show SMILES CCC[C@@H](NC(=O)c1ccc(c(c1)C(O)=O)-c1ccccc1-c1nc2ccccc2[nH]1)c1ccccc1 |r| Show InChI InChI=1S/C31H27N3O3/c1-2-10-26(20-11-4-3-5-12-20)34-30(35)21-17-18-23(25(19-21)31(36)37)22-13-6-7-14-24(22)29-32-27-15-8-9-16-28(27)33-29/h3-9,11-19,26H,2,10H2,1H3,(H,32,33)(H,34,35)(H,36,37)/t26-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	5.70	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Agonist activity at human APJ-R expressed in HEK293 cells assessed as inhibition of forskolin- stimulated cAMP accumulation incubated for 30 mins by ...				J Med Chem 62: 10456-10465 (2019) Article DOI: 10.1021/acs.jmedchem.9b01513
					More data for this Ligand-Target Pair