BDBM50506130 CHEMBL4567816

SMILES: Cc1cccc(Cc2c([nH]c3nc(N)nn3c2=O)C2CC2)c1

InChI Key: InChIKey=YJQISPMIWAOWOU-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50506130   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50506130 (CHEMBL4567816) Show SMILES Cc1cccc(Cc2c([nH]c3nc(N)nn3c2=O)C2CC2)c1 Show InChI InChI=1S/C16H17N5O/c1-9-3-2-4-10(7-9)8-12-13(11-5-6-11)18-16-19-15(17)20-21(16)14(12)22/h2-4,7,11H,5-6,8H2,1H3,(H3,17,18,19,20)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Displacement of [3H]-CCR2-RA-[R] from human CCR2 expressed in human U2OS cells incubated for 2 hrs by scintillation spectrometric method				J Med Chem 62: 11035-11053 (2019) Article DOI: 10.1021/acs.jmedchem.9b00742
					More data for this Ligand-Target Pair
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50506130 (CHEMBL4567816) Show SMILES Cc1cccc(Cc2c([nH]c3nc(N)nn3c2=O)C2CC2)c1 Show InChI InChI=1S/C16H17N5O/c1-9-3-2-4-10(7-9)8-12-13(11-5-6-11)18-16-19-15(17)20-21(16)14(12)22/h2-4,7,11H,5-6,8H2,1H3,(H3,17,18,19,20)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Displacement of [3H]-CCR2-RA-[R] from human CCR2 expressed in human U2OS cells incubated for 2 hrs by scintillation spectrometric method				J Med Chem 62: 11035-11053 (2019) Article DOI: 10.1021/acs.jmedchem.9b00742
					More data for this Ligand-Target Pair