BDBM50506137 CHEMBL4588111

SMILES: CCc1[nH]c2nc(N)nn2c(=O)c1Cc1cccc(Cl)c1

InChI Key: InChIKey=XZXWUTWMPLYWHJ-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50506137   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50506137 (CHEMBL4588111) Show SMILES CCc1[nH]c2nc(N)nn2c(=O)c1Cc1cccc(Cl)c1 Show InChI InChI=1S/C14H14ClN5O/c1-2-11-10(7-8-4-3-5-9(15)6-8)12(21)20-14(17-11)18-13(16)19-20/h3-6H,2,7H2,1H3,(H3,16,17,18,19)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Displacement of [3H]-CCR2-RA-[R] from human CCR2 expressed in human U2OS cells incubated for 2 hrs by scintillation spectrometric method				J Med Chem 62: 11035-11053 (2019) Article DOI: 10.1021/acs.jmedchem.9b00742
					More data for this Ligand-Target Pair
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50506137 (CHEMBL4588111) Show SMILES CCc1[nH]c2nc(N)nn2c(=O)c1Cc1cccc(Cl)c1 Show InChI InChI=1S/C14H14ClN5O/c1-2-11-10(7-8-4-3-5-9(15)6-8)12(21)20-14(17-11)18-13(16)19-20/h3-6H,2,7H2,1H3,(H3,16,17,18,19)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Leiden University Curated by ChEMBL					Assay Description Displacement of [3H]-CCR2-RA-[R] from human CCR2 expressed in human U2OS cells incubated for 2 hrs by scintillation spectrometric method				J Med Chem 62: 11035-11053 (2019) Article DOI: 10.1021/acs.jmedchem.9b00742
					More data for this Ligand-Target Pair