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SMILES: C[C@@H]1NC(=O)C[C@H](O)[C@H](Cc2ccccc2)NC(=O)CCCCCCCCCCCNC1=O

InChI Key: InChIKey=FHOYBWZZOVUMMB-PMVMPFDFSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50506513   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Cathepsin D


(Homo sapiens (Human))		BDBM50506513
PNG
(CHEMBL4465469)
Show SMILES C[C@@H]1NC(=O)C[C@H](O)[C@H](Cc2ccccc2)NC(=O)CCCCCCCCCCCNC1=O |r|
Show InChI InChI=1S/C26H41N3O4/c1-20-26(33)27-17-13-8-6-4-2-3-5-7-12-16-24(31)29-22(23(30)19-25(32)28-20)18-21-14-10-9-11-15-21/h9-11,14-15,20,22-23,30H,2-8,12-13,16-19H2,1H3,(H,27,33)(H,28,32)(H,29,31)/t20-,22-,23-/m0/s1
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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 68n/an/an/an/an/an/a



Czech Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of human placenta CatD using Abz-Lys-Pro-Ala-Glu-Phe-Nph-Ala-Leu as substrate preincubated for 10 mins followed by substrate addition and ...

J Med Chem 63: 1576-1596 (2020)


Article DOI: 10.1021/acs.jmedchem.9b01351
More data for this
Ligand-Target Pair