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BDBM50507220 CHEMBL4578844

SMILES: O=C(CCC1CCN(CC2CCCCC2)CC1)c1ccc2n(Cc3ccccc3)ccc2c1

InChI Key: InChIKey=ICALDSOVJLIENB-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50507220   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Acetylcholinesterase


(Homo sapiens (Human))		BDBM50507220
PNG
(CHEMBL4578844)
Show SMILES O=C(CCC1CCN(CC2CCCCC2)CC1)c1ccc2n(Cc3ccccc3)ccc2c1
Show InChI InChI=1S/C30H38N2O/c33-30(14-11-24-15-18-31(19-16-24)22-25-7-3-1-4-8-25)28-12-13-29-27(21-28)17-20-32(29)23-26-9-5-2-6-10-26/h2,5-6,9-10,12-13,17,20-21,24-25H,1,3-4,7-8,11,14-16,18-19,22-23H2
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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 133n/an/an/an/an/an/a



Normandie Univ

Curated by ChEMBL


Assay Description
Inhibition of human erythrocytes AChE using acetylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition measured at ...

Eur J Med Chem 162: 234-248 (2019)


Article DOI: 10.1016/j.ejmech.2018.10.064
More data for this
Ligand-Target Pair