BDBM50507253 CHEMBL4567832

SMILES: CN(Cc1ccccc1)c1ccc2C(=O)N(CCCCCC(=O)NO)C(=O)c3cccc1c23

InChI Key: InChIKey=XIBYSMPUNMZEDF-UHFFFAOYSA-N

Data: 5 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50507253   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2) (Homo sapiens (Human))	BDBM50507253 (CHEMBL4567832) Show SMILES CN(Cc1ccccc1)c1ccc2C(=O)N(CCCCCC(=O)NO)C(=O)c3cccc1c23 Show InChI InChI=1S/C26H27N3O4/c1-28(17-18-9-4-2-5-10-18)22-15-14-21-24-19(22)11-8-12-20(24)25(31)29(26(21)32)16-7-3-6-13-23(30)27-33/h2,4-5,8-12,14-15,33H,3,6-7,13,16-17H2,1H3,(H,27,30)	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	700	n/a	n/a	n/a	n/a	n/a	n/a
Deakin University Curated by ChEMBL					Assay Description Inhibition of human recombinant full length C-terminal His-tagged HDAC3 (1 to 428 residues)/N-terminal GST-tagged NCOR2 (395 to 489 residues) express...				Eur J Med Chem 162: 321-333 (2019) Article DOI: 10.1016/j.ejmech.2018.11.020
					More data for this Ligand-Target Pair
Cereblon/Histone deacetylase 6 (Homo sapiens (Human))	BDBM50507253 (CHEMBL4567832) Show SMILES CN(Cc1ccccc1)c1ccc2C(=O)N(CCCCCC(=O)NO)C(=O)c3cccc1c23 Show InChI InChI=1S/C26H27N3O4/c1-28(17-18-9-4-2-5-10-18)22-15-14-21-24-19(22)11-8-12-20(24)25(31)29(26(21)32)16-7-3-6-13-23(30)27-33/h2,4-5,8-12,14-15,33H,3,6-7,13,16-17H2,1H3,(H,27,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	9.70	n/a	n/a	n/a	n/a	n/a	n/a
Deakin University Curated by ChEMBL					Assay Description Inhibition of recombinant N-terminal GST-tagged human HDAC6 (1 to 1215 residues) expressed in Baculovirus infected insect cells using RHKK-Ac as subs...				Eur J Med Chem 162: 321-333 (2019) Article DOI: 10.1016/j.ejmech.2018.11.020
					More data for this Ligand-Target Pair
Histone deacetylase 11 (Homo sapiens (Human))	BDBM50507253 (CHEMBL4567832) Show SMILES CN(Cc1ccccc1)c1ccc2C(=O)N(CCCCCC(=O)NO)C(=O)c3cccc1c23 Show InChI InChI=1S/C26H27N3O4/c1-28(17-18-9-4-2-5-10-18)22-15-14-21-24-19(22)11-8-12-20(24)25(31)29(26(21)32)16-7-3-6-13-23(30)27-33/h2,4-5,8-12,14-15,33H,3,6-7,13,16-17H2,1H3,(H,27,30)	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.22E+3	n/a	n/a	n/a	n/a	n/a	n/a
Deakin University Curated by ChEMBL					Assay Description Inhibition of recombinant C-terminal His-tagged human HDAC11 (1 to 347 residues) expressed in Baculovirus infected insect cells using RHKK-Ac as subs...				Eur J Med Chem 162: 321-333 (2019) Article DOI: 10.1016/j.ejmech.2018.11.020
					More data for this Ligand-Target Pair
Histone deacetylase 8 (Homo sapiens (Human))	BDBM50507253 (CHEMBL4567832) Show SMILES CN(Cc1ccccc1)c1ccc2C(=O)N(CCCCCC(=O)NO)C(=O)c3cccc1c23 Show InChI InChI=1S/C26H27N3O4/c1-28(17-18-9-4-2-5-10-18)22-15-14-21-24-19(22)11-8-12-20(24)25(31)29(26(21)32)16-7-3-6-13-23(30)27-33/h2,4-5,8-12,14-15,33H,3,6-7,13,16-17H2,1H3,(H,27,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Deakin University Curated by ChEMBL					Assay Description Inhibition of recombinant C-terminal His-tagged human HDAC8 (1 to 377 residues) expressed in Baculovirus infected insect cells using RHK-K(Ac)-AMC as...				Eur J Med Chem 162: 321-333 (2019) Article DOI: 10.1016/j.ejmech.2018.11.020
					More data for this Ligand-Target Pair
Cereblon/Histone deacetylase 1 (Homo sapiens (Human))	BDBM50507253 (CHEMBL4567832) Show SMILES CN(Cc1ccccc1)c1ccc2C(=O)N(CCCCCC(=O)NO)C(=O)c3cccc1c23 Show InChI InChI=1S/C26H27N3O4/c1-28(17-18-9-4-2-5-10-18)22-15-14-21-24-19(22)11-8-12-20(24)25(31)29(26(21)32)16-7-3-6-13-23(30)27-33/h2,4-5,8-12,14-15,33H,3,6-7,13,16-17H2,1H3,(H,27,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.38E+3	n/a	n/a	n/a	n/a	n/a	n/a
Deakin University Curated by ChEMBL					Assay Description Inhibition of recombinant full length C-terminal FLAG/His-tagged human HDAC1 (1 to 482 residues) expressed in sf21 cells using RHK-K(Ac)-AMC as subst...				Eur J Med Chem 162: 321-333 (2019) Article DOI: 10.1016/j.ejmech.2018.11.020
					More data for this Ligand-Target Pair