BDBM50507428 CHEMBL4567141

SMILES: OC(=O)CNC(=O)c1c(O)c2COCc2n(Cc2cnc(cn2)C(F)(F)F)c1=O

InChI Key: InChIKey=JDLGXHQNBSGCLL-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50507428   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Egl nine homolog 1 (Homo sapiens (Human))	BDBM50507428 (CHEMBL4567141) Show SMILES OC(=O)CNC(=O)c1c(O)c2COCc2n(Cc2cnc(cn2)C(F)(F)F)c1=O Show InChI InChI=1S/C16H13F3N4O6/c17-16(18,19)10-2-20-7(1-21-10)4-23-9-6-29-5-8(9)13(26)12(15(23)28)14(27)22-3-11(24)25/h1-2,26H,3-6H2,(H,22,27)(H,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.90	n/a	n/a	n/a	n/a	n/a	n/a
Merck & Co., Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant human HIF-PHD2 expressed in baculovirus-infected Sf9 cells using biotin labelled DLDLEMLAPYIPMDDDFQL and 2-oxoglutarate as ...				ACS Med Chem Lett 9: 1193-1198 (2018) Article DOI: 10.1021/acsmedchemlett.8b00274
					More data for this Ligand-Target Pair
Prolyl hydroxylase EGLN3 (Homo sapiens (Human))	BDBM50507428 (CHEMBL4567141) Show SMILES OC(=O)CNC(=O)c1c(O)c2COCc2n(Cc2cnc(cn2)C(F)(F)F)c1=O Show InChI InChI=1S/C16H13F3N4O6/c17-16(18,19)10-2-20-7(1-21-10)4-23-9-6-29-5-8(9)13(26)12(15(23)28)14(27)22-3-11(24)25/h1-2,26H,3-6H2,(H,22,27)(H,24,25)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Merck & Co., Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant human HIF-PHD3 expressed in baculovirus-infected Sf9 cells using biotin labelled DLDLEMLAPYIPMDDDFQL and 2-oxoglutarate as ...				ACS Med Chem Lett 9: 1193-1198 (2018) Article DOI: 10.1021/acsmedchemlett.8b00274
					More data for this Ligand-Target Pair
Hypoxia-inducible factor prolyl hydroxylase (Homo sapiens (Human))	BDBM50507428 (CHEMBL4567141) Show SMILES OC(=O)CNC(=O)c1c(O)c2COCc2n(Cc2cnc(cn2)C(F)(F)F)c1=O Show InChI InChI=1S/C16H13F3N4O6/c17-16(18,19)10-2-20-7(1-21-10)4-23-9-6-29-5-8(9)13(26)12(15(23)28)14(27)22-3-11(24)25/h1-2,26H,3-6H2,(H,22,27)(H,24,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.90	n/a	n/a	n/a	n/a	n/a	n/a
Merck & Co., Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant human HIF-PHD1 expressed in baculovirus-infected Sf9 cells using biotin labelled DLDLEMLAPYIPMDDDFQL and 2-oxoglutarate as ...				ACS Med Chem Lett 9: 1193-1198 (2018) Article DOI: 10.1021/acsmedchemlett.8b00274
					More data for this Ligand-Target Pair