BDBM50508193 CHEMBL4514702

SMILES: Cn1ncc2c(cccc12)C(=O)NCc1cccc(c1)C(F)(F)F

InChI Key: InChIKey=LZFDKWQFCBLFIX-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50508193   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 1 (Homo sapiens (Human))	BDBM50508193 (CHEMBL4514702) Show SMILES Cn1ncc2c(cccc12)C(=O)NCc1cccc(c1)C(F)(F)F Show InChI InChI=1S/C17H14F3N3O/c1-23-15-7-3-6-13(14(15)10-22-23)16(24)21-9-11-4-2-5-12(8-11)17(18,19)20/h2-8,10H,9H2,1H3,(H,21,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Curated by ChEMBL					Assay Description Antagonist activity at recombinant CCR1 (unknown origin) expressed in non-adherent cells co-expressing Galpha16 assessed as inhibition of MIP-1 alpha...				Bioorg Med Chem Lett 29: 441-448 (2019) Article DOI: 10.1016/j.bmcl.2018.12.024
					More data for this Ligand-Target Pair