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BDBM50508194 CHEMBL4450029

SMILES: Fc1ccc(cc1)-n1ncc2c(cccc12)C(=O)NCc1ccccc1C(F)(F)F

InChI Key: InChIKey=KEZRBGXATRUGLG-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50508194   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
C-C chemokine receptor type 1


(Homo sapiens (Human))		BDBM50508194
PNG
(CHEMBL4450029)
Show SMILES Fc1ccc(cc1)-n1ncc2c(cccc12)C(=O)NCc1ccccc1C(F)(F)F
Show InChI InChI=1S/C22H15F4N3O/c23-15-8-10-16(11-9-15)29-20-7-3-5-17(18(20)13-28-29)21(30)27-12-14-4-1-2-6-19(14)22(24,25)26/h1-11,13H,12H2,(H,27,30)
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PC cid
PC sid
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Article
PubMed
n/an/a 1.20E+3n/an/an/an/an/an/a



Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL


Assay Description
Antagonist activity at recombinant CCR1 (unknown origin) expressed in non-adherent cells co-expressing Galpha16 assessed as inhibition of MIP-1 alpha...

Bioorg Med Chem Lett 29: 441-448 (2019)


Article DOI: 10.1016/j.bmcl.2018.12.024
More data for this
Ligand-Target Pair