BDBM50508213 CHEMBL4568987

SMILES: Fc1ccc(cc1)-n1ncc2c(cccc12)C(=O)NCc1cccc(Cl)c1

InChI Key: InChIKey=VUJKWDPRLOTRFG-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50508213   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 1 (Homo sapiens (Human))	BDBM50508213 (CHEMBL4568987) Show SMILES Fc1ccc(cc1)-n1ncc2c(cccc12)C(=O)NCc1cccc(Cl)c1 Show InChI InChI=1S/C21H15ClFN3O/c22-15-4-1-3-14(11-15)12-24-21(27)18-5-2-6-20-19(18)13-25-26(20)17-9-7-16(23)8-10-17/h1-11,13H,12H2,(H,24,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	450	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Curated by ChEMBL					Assay Description Antagonist activity at recombinant CCR1 (unknown origin) expressed in non-adherent cells co-expressing Galpha16 assessed as inhibition of MIP-1 alpha...				Bioorg Med Chem Lett 29: 441-448 (2019) Article DOI: 10.1016/j.bmcl.2018.12.024
					More data for this Ligand-Target Pair