BDBM50508214 CHEMBL4475918

SMILES: CN(C)S(=O)(=O)c1ccc(CNC(=O)c2cccc3n(ncc23)-c2ccc(F)cc2)cc1

InChI Key: InChIKey=MAVUMCVBJPRJSR-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50508214   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 1 (Homo sapiens (Human))	BDBM50508214 (CHEMBL4475918) Show SMILES CN(C)S(=O)(=O)c1ccc(CNC(=O)c2cccc3n(ncc23)-c2ccc(F)cc2)cc1 Show InChI InChI=1S/C23H21FN4O3S/c1-27(2)32(30,31)19-12-6-16(7-13-19)14-25-23(29)20-4-3-5-22-21(20)15-26-28(22)18-10-8-17(24)9-11-18/h3-13,15H,14H2,1-2H3,(H,25,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim Pharmaceuticals Curated by ChEMBL					Assay Description Antagonist activity at recombinant CCR1 (unknown origin) expressed in non-adherent cells co-expressing Galpha16 assessed as inhibition of MIP-1 alpha...				Bioorg Med Chem Lett 29: 441-448 (2019) Article DOI: 10.1016/j.bmcl.2018.12.024
					More data for this Ligand-Target Pair