null
SMILES: Cc1cc2c(NC(=O)C=C)cccc2n1-c1nc2CCOCc2c(NCc2ccccc2)n1
InChI Key: InChIKey=CJLYSVHXDHBDEJ-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Transitional endoplasmic reticulum ATPase (Homo sapiens (Human)) | BDBM50508305 (CHEMBL4453010) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 27 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Minnesota Curated by ChEMBL | Assay Description Inhibition of His-tagged p97 (unknown origin) in presence of ATP and PNP by UV-transparent microplate assay | J Med Chem 62: 2814-2829 (2019) Article DOI: 10.1021/acs.jmedchem.9b00144 BindingDB Entry DOI: 10.7270/Q24171H0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transitional endoplasmic reticulum ATPase (Homo sapiens (Human)) | BDBM50508305 (CHEMBL4453010) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 58 | n/a | n/a | n/a | n/a | n/a | n/a |
Nanjing Normal University Curated by ChEMBL | Assay Description Inhibition of human p97 using ATP as substrate after 60 mins by ADP-Glo assay | Bioorg Med Chem 27: 533-544 (2019) Article DOI: 10.1016/j.bmc.2018.12.036 BindingDB Entry DOI: 10.7270/Q2RX9GDB | |||||||||||
More data for this Ligand-Target Pair |