BDBM50508353 CHEMBL4462068

SMILES: Clc1ccc(cc1Cl)-c1ccc(o1)C(=O)N1CCN(Cc2ccc(OC3CCNCC3)c(Cl)c2)CC1

InChI Key: InChIKey=CUAMUUBGLLLICA-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50508353   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Urotensin II receptor (Homo sapiens (Human))	BDBM50508353 (CHEMBL4462068) Show SMILES Clc1ccc(cc1Cl)-c1ccc(o1)C(=O)N1CCN(Cc2ccc(OC3CCNCC3)c(Cl)c2)CC1 Show InChI InChI=1S/C27H28Cl3N3O3/c28-21-3-2-19(16-22(21)29)24-5-6-26(36-24)27(34)33-13-11-32(12-14-33)17-18-1-4-25(23(30)15-18)35-20-7-9-31-10-8-20/h1-6,15-16,20,31H,7-14,17H2	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	240	n/a	n/a	n/a	n/a	n/a	n/a
Korea Research Institute of Chemical Technology Curated by ChEMBL					Assay Description Antagonist activity at human UT2 receptor expressed in HEK293-aeq cells assessed as inhibition of U2-induced intracellular calcium mobilization prein...				Bioorg Med Chem Lett 29: 577-580 (2019) Article DOI: 10.1016/j.bmcl.2018.12.058
					More data for this Ligand-Target Pair
Urotensin II receptor (Homo sapiens (Human))	BDBM50508353 (CHEMBL4462068) Show SMILES Clc1ccc(cc1Cl)-c1ccc(o1)C(=O)N1CCN(Cc2ccc(OC3CCNCC3)c(Cl)c2)CC1 Show InChI InChI=1S/C27H28Cl3N3O3/c28-21-3-2-19(16-22(21)29)24-5-6-26(36-24)27(34)33-13-11-32(12-14-33)17-18-1-4-25(23(30)15-18)35-20-7-9-31-10-8-20/h1-6,15-16,20,31H,7-14,17H2	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	38	n/a	n/a	n/a	n/a	n/a	n/a
Korea Research Institute of Chemical Technology Curated by ChEMBL					Assay Description Displacement of Eu-labelled UT2 from recombinant human UT2 receptor expressed in HEK293 cell membranes preincubated for 10 mins followed by Eu-labell...				Bioorg Med Chem Lett 29: 577-580 (2019) Article DOI: 10.1016/j.bmcl.2018.12.058
					More data for this Ligand-Target Pair