BDBM50508359 CHEMBL4449461

SMILES: Clc1cc(CN2CCN(CC2)C(=O)c2ccc(o2)-c2cccc(c2)-c2ccccc2)ccc1OC1CCNCC1

InChI Key: InChIKey=JDZJYZOGPIYDOH-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50508359   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Urotensin II receptor (Homo sapiens (Human))	BDBM50508359 (CHEMBL4449461) Show SMILES Clc1cc(CN2CCN(CC2)C(=O)c2ccc(o2)-c2cccc(c2)-c2ccccc2)ccc1OC1CCNCC1 Show InChI InChI=1S/C33H34ClN3O3/c34-29-21-24(9-10-31(29)39-28-13-15-35-16-14-28)23-36-17-19-37(20-18-36)33(38)32-12-11-30(40-32)27-8-4-7-26(22-27)25-5-2-1-3-6-25/h1-12,21-22,28,35H,13-20,23H2	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
Korea Research Institute of Chemical Technology Curated by ChEMBL					Assay Description Displacement of Eu-labelled UT2 from recombinant human UT2 receptor expressed in HEK293 cell membranes preincubated for 10 mins followed by Eu-labell...				Bioorg Med Chem Lett 29: 577-580 (2019) Article DOI: 10.1016/j.bmcl.2018.12.058
					More data for this Ligand-Target Pair
Urotensin II receptor (Homo sapiens (Human))	BDBM50508359 (CHEMBL4449461) Show SMILES Clc1cc(CN2CCN(CC2)C(=O)c2ccc(o2)-c2cccc(c2)-c2ccccc2)ccc1OC1CCNCC1 Show InChI InChI=1S/C33H34ClN3O3/c34-29-21-24(9-10-31(29)39-28-13-15-35-16-14-28)23-36-17-19-37(20-18-36)33(38)32-12-11-30(40-32)27-8-4-7-26(22-27)25-5-2-1-3-6-25/h1-12,21-22,28,35H,13-20,23H2	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	470	n/a	n/a	n/a	n/a	n/a	n/a
Korea Research Institute of Chemical Technology Curated by ChEMBL					Assay Description Antagonist activity at human UT2 receptor expressed in HEK293-aeq cells assessed as inhibition of U2-induced intracellular calcium mobilization prein...				Bioorg Med Chem Lett 29: 577-580 (2019) Article DOI: 10.1016/j.bmcl.2018.12.058
					More data for this Ligand-Target Pair