BDBM50508364 CHEMBL4529337

SMILES: Fc1ccc(F)c(c1)-c1ccc(o1)C(=O)N1CCN(Cc2ccc(OC3CCNCC3)c(Cl)c2)CC1

InChI Key: InChIKey=HYXSEYTYPJTOLB-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50508364   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Urotensin II receptor (Homo sapiens (Human))	BDBM50508364 (CHEMBL4529337) Show SMILES Fc1ccc(F)c(c1)-c1ccc(o1)C(=O)N1CCN(Cc2ccc(OC3CCNCC3)c(Cl)c2)CC1 Show InChI InChI=1S/C27H28ClF2N3O3/c28-22-15-18(1-4-25(22)35-20-7-9-31-10-8-20)17-32-11-13-33(14-12-32)27(34)26-6-5-24(36-26)21-16-19(29)2-3-23(21)30/h1-6,15-16,20,31H,7-14,17H2	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
Korea Research Institute of Chemical Technology Curated by ChEMBL					Assay Description Displacement of Eu-labelled UT2 from recombinant human UT2 receptor expressed in HEK293 cell membranes preincubated for 10 mins followed by Eu-labell...				Bioorg Med Chem Lett 29: 577-580 (2019) Article DOI: 10.1016/j.bmcl.2018.12.058
					More data for this Ligand-Target Pair
Urotensin II receptor (Homo sapiens (Human))	BDBM50508364 (CHEMBL4529337) Show SMILES Fc1ccc(F)c(c1)-c1ccc(o1)C(=O)N1CCN(Cc2ccc(OC3CCNCC3)c(Cl)c2)CC1 Show InChI InChI=1S/C27H28ClF2N3O3/c28-22-15-18(1-4-25(22)35-20-7-9-31-10-8-20)17-32-11-13-33(14-12-32)27(34)26-6-5-24(36-26)21-16-19(29)2-3-23(21)30/h1-6,15-16,20,31H,7-14,17H2	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	260	n/a	n/a	n/a	n/a	n/a	n/a
Korea Research Institute of Chemical Technology Curated by ChEMBL					Assay Description Antagonist activity at human UT2 receptor expressed in HEK293-aeq cells assessed as inhibition of U2-induced intracellular calcium mobilization prein...				Bioorg Med Chem Lett 29: 577-580 (2019) Article DOI: 10.1016/j.bmcl.2018.12.058
					More data for this Ligand-Target Pair