BDBM50508377 CHEMBL4546510

SMILES: Cc1ccccc1-c1ccc(o1)C(=O)N1CCN(Cc2ccc(OC3CCNCC3)c(Cl)c2)CC1

InChI Key: InChIKey=CGGQNCJPNWJENQ-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50508377   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Urotensin II receptor (Homo sapiens (Human))	BDBM50508377 (CHEMBL4546510) Show SMILES Cc1ccccc1-c1ccc(o1)C(=O)N1CCN(Cc2ccc(OC3CCNCC3)c(Cl)c2)CC1 Show InChI InChI=1S/C28H32ClN3O3/c1-20-4-2-3-5-23(20)25-8-9-27(35-25)28(33)32-16-14-31(15-17-32)19-21-6-7-26(24(29)18-21)34-22-10-12-30-13-11-22/h2-9,18,22,30H,10-17,19H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
Korea Research Institute of Chemical Technology Curated by ChEMBL					Assay Description Displacement of Eu-labelled UT2 from recombinant human UT2 receptor expressed in HEK293 cell membranes preincubated for 10 mins followed by Eu-labell...				Bioorg Med Chem Lett 29: 577-580 (2019) Article DOI: 10.1016/j.bmcl.2018.12.058
					More data for this Ligand-Target Pair
Urotensin II receptor (Homo sapiens (Human))	BDBM50508377 (CHEMBL4546510) Show SMILES Cc1ccccc1-c1ccc(o1)C(=O)N1CCN(Cc2ccc(OC3CCNCC3)c(Cl)c2)CC1 Show InChI InChI=1S/C28H32ClN3O3/c1-20-4-2-3-5-23(20)25-8-9-27(35-25)28(33)32-16-14-31(15-17-32)19-21-6-7-26(24(29)18-21)34-22-10-12-30-13-11-22/h2-9,18,22,30H,10-17,19H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
Korea Research Institute of Chemical Technology Curated by ChEMBL					Assay Description Antagonist activity at human UT2 receptor expressed in HEK293-aeq cells assessed as inhibition of U2-induced intracellular calcium mobilization prein...				Bioorg Med Chem Lett 29: 577-580 (2019) Article DOI: 10.1016/j.bmcl.2018.12.058
					More data for this Ligand-Target Pair