BindingDB logo
myBDB logout

BDBM50508590 CHEMBL4585980

SMILES: COc1ccc(cc1OC)C(=O)c1sc2nc(C)ccc2c1N

InChI Key: InChIKey=FSGYOGWODNMGAT-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50508590   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Maternal embryonic leucine zipper kinase


(Homo sapiens (Human))		BDBM50508590
PNG
(CHEMBL4585980)
Show SMILES COc1ccc(cc1OC)C(=O)c1sc2nc(C)ccc2c1N
Show InChI InChI=1S/C17H16N2O3S/c1-9-4-6-11-14(18)16(23-17(11)19-9)15(20)10-5-7-12(21-2)13(8-10)22-3/h4-8H,18H2,1-3H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem
Article
PubMed
n/an/a>5.00E+3n/an/an/an/an/an/a



Selvita S.A

Curated by ChEMBL


Assay Description
Inhibition of recombinant human MELK expressed in Escherichia coli using ZIPtide as substrate measured after 0.5 hrs by ADP-Glo assay

Bioorg Med Chem Lett 29: 607-613 (2019)


Article DOI: 10.1016/j.bmcl.2018.12.051
More data for this
Ligand-Target Pair