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BDBM50508591 CHEMBL4460795

SMILES: CC(C)Nc1nc(N)c(s1)C(=O)c1ccc(Cl)s1

InChI Key: InChIKey=RZFMOGPIUUATIZ-UHFFFAOYSA-N

Data: 1 IC50

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50508591   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Maternal embryonic leucine zipper kinase


(Homo sapiens (Human))		BDBM50508591
PNG
(CHEMBL4460795)
Show SMILES CC(C)Nc1nc(N)c(s1)C(=O)c1ccc(Cl)s1
Show InChI InChI=1S/C11H12ClN3OS2/c1-5(2)14-11-15-10(13)9(18-11)8(16)6-3-4-7(12)17-6/h3-5H,13H2,1-2H3,(H,14,15)
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PC cid
PC sid
UniChem
Article
PubMed
n/an/a>5.00E+3n/an/an/an/an/an/a



Selvita S.A

Curated by ChEMBL


Assay Description
Inhibition of recombinant human MELK expressed in Escherichia coli using ZIPtide as substrate measured after 0.5 hrs by ADP-Glo assay

Bioorg Med Chem Lett 29: 607-613 (2019)


Article DOI: 10.1016/j.bmcl.2018.12.051
More data for this
Ligand-Target Pair