BDBM50508597 CHEMBL4560455

SMILES: CC(C)Nc1sc(C(=O)c2cccnc2)c(N)c1C#N

InChI Key: InChIKey=YDBPEJRIWWAMTG-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50508597   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Maternal embryonic leucine zipper kinase (Homo sapiens (Human))	BDBM50508597 (CHEMBL4560455) Show SMILES CC(C)Nc1sc(C(=O)c2cccnc2)c(N)c1C#N Show InChI InChI=1S/C14H14N4OS/c1-8(2)18-14-10(6-15)11(16)13(20-14)12(19)9-4-3-5-17-7-9/h3-5,7-8,18H,16H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Selvita S.A Curated by ChEMBL					Assay Description Inhibition of recombinant human MELK expressed in Escherichia coli using ZIPtide as substrate measured after 0.5 hrs by ADP-Glo assay				Bioorg Med Chem Lett 29: 607-613 (2019) Article DOI: 10.1016/j.bmcl.2018.12.051
					More data for this Ligand-Target Pair