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BDBM50508604 CHEMBL4538177

SMILES: CC(C)Nc1sc(C(=O)c2cc(Cl)cs2)c(N)c1C#N

InChI Key: InChIKey=MOJNPFHPESDTIG-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50508604   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Maternal embryonic leucine zipper kinase


(Homo sapiens (Human))		BDBM50508604
PNG
(CHEMBL4538177)
Show SMILES CC(C)Nc1sc(C(=O)c2cc(Cl)cs2)c(N)c1C#N
Show InChI InChI=1S/C13H12ClN3OS2/c1-6(2)17-13-8(4-15)10(16)12(20-13)11(18)9-3-7(14)5-19-9/h3,5-6,17H,16H2,1-2H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 575n/an/an/an/an/an/a



Selvita S.A

Curated by ChEMBL


Assay Description
Inhibition of recombinant human MELK expressed in Escherichia coli using ZIPtide as substrate measured after 0.5 hrs by ADP-Glo assay

Bioorg Med Chem Lett 29: 607-613 (2019)


Article DOI: 10.1016/j.bmcl.2018.12.051
More data for this
Ligand-Target Pair