BDBM50508784 CHEMBL4543868

SMILES: CCCn1c2c(Oc3cc(Cl)cc(c3)C#N)cccc2[nH]c1=O

InChI Key: InChIKey=LFYWPMJWZMLUDM-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50508784   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50508784 (CHEMBL4543868) Show SMILES CCCn1c2c(Oc3cc(Cl)cc(c3)C#N)cccc2[nH]c1=O Show InChI InChI=1S/C17H14ClN3O2/c1-2-6-21-16-14(20-17(21)22)4-3-5-15(16)23-13-8-11(10-19)7-12(18)9-13/h3-5,7-9H,2,6H2,1H3,(H,20,22)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Stellenbosch University Curated by ChEMBL					Assay Description Inhibition of wild-type HIV1 reverse transcriptase in HIV1 infected HEK293T cells harboring luciferase gene assessed as reduction in viral infection ...				ACS Med Chem Lett 10: 196-202 (2019) Article DOI: 10.1021/acsmedchemlett.8b00549
					More data for this Ligand-Target Pair