BDBM50509003 CHEMBL4556601

SMILES: N[C@]1(CN(C[C@H]2COCCN2)C[C@@H]1CCCB(O)O)C(O)=O

InChI Key: InChIKey=KBOTZNVDRDMHLL-GVXVVHGQSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50509003   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Arginase-1 (Homo sapiens (Human))	BDBM50509003 (CHEMBL4556601) Show SMILES N[C@]1(CN(C[C@H]2COCCN2)C[C@@H]1CCCB(O)O)C(O)=O |r| Show InChI InChI=1S/C13H26BN3O5/c15-13(12(18)19)9-17(7-11-8-22-5-4-16-11)6-10(13)2-1-3-14(20)21/h10-11,16,20-21H,1-9,15H2,(H,18,19)/t10-,11-,13-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
New England Discovery Partners Curated by ChEMBL					Assay Description Inhibition of human recombinant arginase 1 expressed in Escherichia coli BL21 (DE3) assessed as reduction in urea production using L-arginine as subs...				J Med Chem 62: 8164-8177 (2019) Article DOI: 10.1021/acs.jmedchem.9b00931
					More data for this Ligand-Target Pair