null

SMILES: COc1cccc(CN(C)C(=O)Cn2c3ccccc3c3cc(ccc23)-c2cccc(Cl)c2)c1

InChI Key: InChIKey=UOVOFLCXPYUNBF-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50509023   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Translocator protein (Homo sapiens (Human))	BDBM50509023 (CHEMBL4535242) Show SMILES COc1cccc(CN(C)C(=O)Cn2c3ccccc3c3cc(ccc23)-c2cccc(Cl)c2)c1 Show InChI InChI=1S/C29H25ClN2O2/c1-31(18-20-7-5-10-24(15-20)34-2)29(33)19-32-27-12-4-3-11-25(27)26-17-22(13-14-28(26)32)21-8-6-9-23(30)16-21/h3-17H,18-19H2,1-2H3	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	201	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Macquarie University Curated by ChEMBL					Assay Description Displacement of [3H]PK11195 from wild-type human TSPO expressed in HEK293 cell membranes after 90 mins by scintillation counting method				J Med Chem 62: 8235-8248 (2019) Article DOI: 10.1021/acs.jmedchem.9b00980
					More data for this Ligand-Target Pair
Translocator protein (Homo sapiens (Human))	BDBM50509023 (CHEMBL4535242) Show SMILES COc1cccc(CN(C)C(=O)Cn2c3ccccc3c3cc(ccc23)-c2cccc(Cl)c2)c1 Show InChI InChI=1S/C29H25ClN2O2/c1-31(18-20-7-5-10-24(15-20)34-2)29(33)19-32-27-12-4-3-11-25(27)26-17-22(13-14-28(26)32)21-8-6-9-23(30)16-21/h3-17H,18-19H2,1-2H3	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	639	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Macquarie University Curated by ChEMBL					Assay Description Displacement of [3H]PK11195 from human TSPO A147T mutant expressed in HEK293 cell membranes after 90 mins by scintillation counting method				J Med Chem 62: 8235-8248 (2019) Article DOI: 10.1021/acs.jmedchem.9b00980
					More data for this Ligand-Target Pair