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SMILES: CCN(Cc1ccc(F)cc1)C(=O)Cn1c2ccccc2c2ccccc12

InChI Key: InChIKey=SENZHCJSQXTVHU-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50509026   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Translocator protein


(Homo sapiens (Human))		BDBM50509026
PNG
(CHEMBL4551915)
Show SMILES CCN(Cc1ccc(F)cc1)C(=O)Cn1c2ccccc2c2ccccc12
Show InChI InChI=1S/C23H21FN2O/c1-2-25(15-17-11-13-18(24)14-12-17)23(27)16-26-21-9-5-3-7-19(21)20-8-4-6-10-22(20)26/h3-14H,2,15-16H2,1H3
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
 694n/an/an/an/an/an/an/an/a



Macquarie University

Curated by ChEMBL


Assay Description
Displacement of [3H]PK11195 from wild-type human TSPO expressed in HEK293 cell membranes after 90 mins by scintillation counting method

J Med Chem 62: 8235-8248 (2019)


Article DOI: 10.1021/acs.jmedchem.9b00980
More data for this
Ligand-Target Pair
Translocator protein


(Homo sapiens (Human))		BDBM50509026
PNG
(CHEMBL4551915)
Show SMILES CCN(Cc1ccc(F)cc1)C(=O)Cn1c2ccccc2c2ccccc12
Show InChI InChI=1S/C23H21FN2O/c1-2-25(15-17-11-13-18(24)14-12-17)23(27)16-26-21-9-5-3-7-19(21)20-8-4-6-10-22(20)26/h3-14H,2,15-16H2,1H3
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



Macquarie University

Curated by ChEMBL


Assay Description
Displacement of [3H]PK11195 from human TSPO A147T mutant expressed in HEK293 cell membranes after 90 mins by scintillation counting method

J Med Chem 62: 8235-8248 (2019)


Article DOI: 10.1021/acs.jmedchem.9b00980
More data for this
Ligand-Target Pair